Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research 6-том 6-сан (2025)

THE ROLE OF HYPERHOMOCYSTEINEMIA IN THE PATHOGENESIS OF POST-TRAUMATIC ENCEPHALOPATHY

Хайдаров Нодир Қодирович, Хикматова Шахзода Шухратовна, Собирова Саодат Кароматовна

Булактан окуу PDF

Аннотация

Post-traumatic encephalopathy (PTE) is one of the most frequent and socially significant consequences of craniocerebral trauma, accompanied by cognitive and emotional impairments. In recent years, special attention has been paid to the study of biochemical markers that reflect the severity of the pathological process and the prognosis of recovery. The aim of the study was to determine the role of hyperhomocysteinemia in the pathogenesis of PTE and its relationship with cognitive impairments. 60 patients treated at the Tashkent Regional Specialized Somatic Hospital were examined. Men predominated in the study sample (66.6%). All patients underwent blood homocysteine levels and neuropsychological testing using the MMSE and MoCA scales. It has been established that higher levels of homocysteine are associated with more pronounced cognitive deficit. A negative correlation was found between homocysteine concentration and cognitive test results. The obtained data confirm the role of hyperhomocysteinemia as a significant biomarker of post-traumatic encephalopathy and indicate the need to determine it in a comprehensive examination of patients.

посттравматическая энцефалопатия; черепно-мозговая травма; гипергомоцистеинемия; когнитивные нарушения; биохимические маркеры; Mini-Mental State Examination (MMSE); Montreal Cognitive Assessment (MoCA)post-traumatic encephalopathy; craniocerebral trauma; hyperhomocysteinemia; cognitive impairments; biochemical markers; Mini- Mental State Examination (MMSE); Montreal Cognitive Assessment (MoCA)посттравматик энцефалопатия; бош мия жароҳати; гипергомотсистеинемия; когнитив бузилишлар; биокимёвий маркерлар; Mini-Mental State Examination (ММСЕ); Montreal Cognitive Assessment (МоCА).

Метадайындар булагы: журналдын OAI-PMH архиви · Sindex толук текстти сактабайт, булакка шилтеме берет.

Цитата алуу

APA 7 
Хайдаров Нодир Қодирович, Хикматова Шахзода Шухратовна & Собирова Саодат Кароматовна (2025). THE ROLE OF HYPERHOMOCYSTEINEMIA IN THE PATHOGENESIS OF POST-TRAUMATIC ENCEPHALOPATHY. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6).
GOST R 7.0.5 
Хайдаров Нодир Қодирович, Хикматова Шахзода Шухратовна, Собирова Саодат Кароматовна THE ROLE OF HYPERHOMOCYSTEINEMIA IN THE PATHOGENESIS OF POST-TRAUMATIC ENCEPHALOPATHY // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. 2025. Т. 6. № 6.
BibTeX 
@article{қодирович2025,
  author  = {Хайдаров Нодир Қодирович and Хикматова Шахзода Шухратовна and Собирова Саодат Кароматовна},
  title   = {THE ROLE OF HYPERHOMOCYSTEINEMIA IN THE PATHOGENESIS OF POST-TRAUMATIC ENCEPHALOPATHY},
  journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
  year    = {2025},
  volume  = {6},
  number  = {6}
}
RIS 
TY  - JOUR
AU  - Хайдаров Нодир Қодирович
AU  - Хикматова Шахзода Шухратовна
AU  - Собирова Саодат Кароматовна
TI  - THE ROLE OF HYPERHOMOCYSTEINEMIA IN THE PATHOGENESIS OF POST-TRAUMATIC ENCEPHALOPATHY
JO  - Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research
PY  - 2025
VL  - 6
IS  - 6
ER  -