Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research Том 7 № 3 (2026)
NEUROLOGICAL MANIFESTATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS: SPECTRUM OF INVOLVEMENT, PATHOGENESIS, DIAGNOSIS AND TREATMENT APPROACHES (Literature Review)
Фахмитдин Хайритдинович Муратов, Шахноза Шохимардоновна Кузиева
Аннотация
Neurological manifestations in systemic lupus erythematosus (SLE) represent one of the most common and clinically significant complications of the disease, reflecting involvement of both the central and peripheral nervous systems. These manifestations encompass a wide spectrum of symptoms, ranging from cognitive impairment and seizures to cerebrovascular and psychiatric disorders. The pathogenesis is multifactorial and involves autoimmune inflammation, vasculopathy, and thrombotic mechanisms [3,4]. Diagnosis requires a comprehensive approach integrating clinical, instrumental, and laboratory methods. Treatment is based on the underlying pathogenic mechanisms and includes both immunosuppressive and symptomatic therapies [2,11].
системная красная волчанка; поражение нервной системы; нейропсихическая СКВ; центральная нервная система; периферическая нервная системаsystemic lupus erythematosus; nervous system involvement; neuropsychiatric systemic lupus erythematosus; central nervous system; peripheral nervous systemtizimli qizil bo’richa; asab tizimi zararlanishi; neyropsixik tizimli qizil bo’richa; markaziy asab tizimi; periferik asab tizimi.
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