Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research Volume 7 Issue 4 (2026)
NEUROLOGICAL DISORDERS IN HEMATOLOGICAL MALIGNANCIES: A COMPARATIVE ANALYSIS
Самандарова Мая Исматиллаевна, Маджидова Якутхон Набиевна
Abstract
Objective: To study the frequency and characteristics of neurological disorders in patients with various hematological malignancies. Materials and Methods: A prospective study was conducted involving 111 patients with hematological malignancies: acute lymphoblastic leukemia (ALL, n=64), acute myeloid leukemia (AML, n=28), and lymphoma (n=19). Cognitive impairment, attention deficit, headache, peripheral neuropathy, movement coordination disorders, and autonomic dystonia were assessed. Results: Cognitive impairment was significantly more common in patients with ALL (63.5±6.2%) compared to AML (57.1±8.6%) and lymphoma (38.5±14.6%) (p<0.001). Other neurological manifestations did not demonstrate statistically significant differences between the groups (p>0.05). Conclusion: Patients with ALL have the highest risk of developing cognitive impairment, which requires special consideration when planning therapeutic and rehabilitation measures.
неврологические нарушения, гематологические злокачественные новообразования, острый лимфобластный лейкоз, острый миелоидный лейкоз, лимфома, когнитивные нарушения: opioid, neuropsychological changes, cognitive disorder, emotional disorder, addiction, rehabilitationnevrologik buzilishlar, gematologik xavfli o‘smalar, o‘tkir limfoblast leykoz, o‘tkir miyeloid leykoz, limfoma, kognitiv buzilishlar
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