Вестник Ассоциации пульмонологов Центральной Азии Volume 15 Issue 10 (2025) · pp. 392-396

THE ROLE OF GENOTYPE COMBINATIONS OF CANDIDATE GENES (TNF-Α, IL-6, SOD2, AND IL-1) IN PREDICTING DERMATOPATHIES IN OBESE PATIENTS

Mirsaidova U.A.

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Abstract

In this population, polymorphisms TNF-α (G308A), IL-6 (C174G), and SOD2 (Ala16Val), as well as their combinations, were associated with an increased risk of dermatopathies in obese patients. The most significant predictive value was observed for the IL-6 + SOD2 combination, particularly in psoriasis. The IL-1 (C511T) polymorphism showed no significant role. These findings confirm the multifactorial nature of pathogenesis and emphasize the importance of genetic interactions in predicting and diagnosing dermatopathies in obesity.

obesity, polymorphism, genes, psoriasis, vitiligo

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Cite

APA 7 
Mirsaidova U.A. (2025). THE ROLE OF GENOTYPE COMBINATIONS OF CANDIDATE GENES (TNF-Α, IL-6, SOD2, AND IL-1) IN PREDICTING DERMATOPATHIES IN OBESE PATIENTS. Вестник Ассоциации пульмонологов Центральной Азии, 15(10), 392-396.
GOST R 7.0.5 
Mirsaidova U.A. THE ROLE OF GENOTYPE COMBINATIONS OF CANDIDATE GENES (TNF-Α, IL-6, SOD2, AND IL-1) IN PREDICTING DERMATOPATHIES IN OBESE PATIENTS // Вестник Ассоциации пульмонологов Центральной Азии. 2025. Т. 15. № 10. С. 392-396.
BibTeX 
@article{u.a.2025,
  author  = {Mirsaidova U.A.},
  title   = {THE ROLE OF GENOTYPE COMBINATIONS OF CANDIDATE GENES (TNF-Α, IL-6, SOD2, AND IL-1) IN PREDICTING DERMATOPATHIES IN OBESE PATIENTS},
  journal = {Вестник Ассоциации пульмонологов Центральной Азии},
  year    = {2025},
  volume  = {15},
  number  = {10},
  pages   = {392-396}
}
RIS 
TY  - JOUR
AU  - Mirsaidova U.A.
TI  - THE ROLE OF GENOTYPE COMBINATIONS OF CANDIDATE GENES (TNF-Α, IL-6, SOD2, AND IL-1) IN PREDICTING DERMATOPATHIES IN OBESE PATIENTS
JO  - Вестник Ассоциации пульмонологов Центральной Азии
PY  - 2025
VL  - 15
IS  - 10
SP  - 392
EP  - 396
ER  -