Klinik fanlar yilnomasi 3-tom 1-san (2026)

PATHOMORPHOLOGICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF BRUCELLOSIS IN AN IMMUNIZED EXPERIMENTAL RABBIT MODEL

Юсупов Акмал Пулатович, Кузиев Отабек Журакулович

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Annotaciya

Pathomorphological changes in the liver under the influence of the live vaccine of Brucella abortus 19 strain were studied in an immunized experimental rabbit model. 12 rabbits (weighing 3.0–3.5 kg) were divided into 4 groups and immunized four times using different schemes (with and without incomplete Freund’s adjuvant). Histological examination of the liver (hematoxylin-eosin staining) showed focal lympho-histiocytic infiltrates, microgranulomas, activation of Kupffer cells, hepatocyte vacuolization, and an increase in the proportion of binucleated hepatocytes (up to 25–35%). These changes confirm the immunogenicity of the Brucella abortus 19 strain and the leading role of the liver in the pathogenesis of brucellosis.

Brucella abortus 19, brucellosis, immunization, strainBrucella abortus 19, бруцеллез, иммунизация, штаммBrucella abortus 19, brutsellyoz, immunizatsiya, shtamm

Metadata derekkózi: jurnal OAI-PMH arxivi · Sindex tolıq mátindi saqlamaydı, derekkózge silteme beredi.

Dáyeksóz alıw

APA 7 
Юсупов Акмал Пулатович & Кузиев Отабек Журакулович (2026). PATHOMORPHOLOGICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF BRUCELLOSIS IN AN IMMUNIZED EXPERIMENTAL RABBIT MODEL. Klinik fanlar yilnomasi, 3(1).
GOST R 7.0.5 
Юсупов Акмал Пулатович, Кузиев Отабек Журакулович PATHOMORPHOLOGICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF BRUCELLOSIS IN AN IMMUNIZED EXPERIMENTAL RABBIT MODEL // Klinik fanlar yilnomasi. 2026. Т. 3. № 1.
BibTeX 
@article{пулатович2026,
  author  = {Юсупов Акмал Пулатович and Кузиев Отабек Журакулович},
  title   = {PATHOMORPHOLOGICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF BRUCELLOSIS IN AN IMMUNIZED EXPERIMENTAL RABBIT MODEL},
  journal = {Klinik fanlar yilnomasi},
  year    = {2026},
  volume  = {3},
  number  = {1}
}
RIS 
TY  - JOUR
AU  - Юсупов Акмал Пулатович
AU  - Кузиев Отабек Журакулович
TI  - PATHOMORPHOLOGICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF BRUCELLOSIS IN AN IMMUNIZED EXPERIMENTAL RABBIT MODEL
JO  - Klinik fanlar yilnomasi
PY  - 2026
VL  - 3
IS  - 1
ER  -