Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali Том 4 № 4 (2023)

Study of the Clinical Efficacy of Oral Direct Anticoagulants in Patients with Atrial Fibrillation

Исмаилов Джамшид Абдураимович, Хамраев Фарид Хамидуллаевич, Хамидуллаев Фирдавс Фаридович, Расули Фарида Орифовна, Тураев Хикматилла Негматович

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Аннотация

To study the clinical efficacy and safety of direct-acting oral anticoagulants in patients with atrial fibrillation treated in a real clinical setting. In this study, 356 AF patients aged 50 to 75 years with a creatinine clearance rate of at least 50 ml/min were observed. Patients were divided into 3 groups according to the type of POAC taken: Group 1 (n=120) took rivaroxaban at a dose of 20 mg/1 g/day; Group 2 (n=112) took dabigatran etexilate at a dose of 150 g/day mg/1 g/day 2 times a day; and Group 3 (n=124) took apixaban at a dose of 5 mg/2 times a day. The groups of patients were compared by age, concomitant pathology, risk of thromboembolic and hemorrhagic complications. The study period was 2 years from the time of drug administration. The endpoints were thromboembolic complications, major bleeding events and death from any cause.

фибрилляция предсердийпероральные антикоагулянтытромбоэмболические осложненияинфарктинсультatrial fibrillationoral anticoagulantsthromboembolic complicationsinfarctionstroke

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APA 7 
Исмаилов Джамшид Абдураимович, Хамраев Фарид Хамидуллаевич, Хамидуллаев Фирдавс Фаридович, Расули Фарида Орифовна & Тураев Хикматилла Негматович (2023). Study of the Clinical Efficacy of Oral Direct Anticoagulants in Patients with Atrial Fibrillation. Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali, 4(4).
GOST R 7.0.5 
Исмаилов Джамшид Абдураимович, Хамраев Фарид Хамидуллаевич, Хамидуллаев Фирдавс Фаридович, Расули Фарида Орифовна, Тураев Хикматилла Негматович Study of the Clinical Efficacy of Oral Direct Anticoagulants in Patients with Atrial Fibrillation // Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali. 2023. Т. 4. № 4.
BibTeX 
@article{абдураимович2023,
  author  = {Исмаилов Джамшид Абдураимович and Хамраев Фарид Хамидуллаевич and Хамидуллаев Фирдавс Фаридович and Расули Фарида Орифовна and Тураев Хикматилла Негматович},
  title   = {Study of the Clinical Efficacy of Oral Direct Anticoagulants in Patients with Atrial Fibrillation},
  journal = {Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali},
  year    = {2023},
  volume  = {4},
  number  = {4}
}
RIS 
TY  - JOUR
AU  - Исмаилов Джамшид Абдураимович
AU  - Хамраев Фарид Хамидуллаевич
AU  - Хамидуллаев Фирдавс Фаридович
AU  - Расули Фарида Орифовна
AU  - Тураев Хикматилла Негматович
TI  - Study of the Clinical Efficacy of Oral Direct Anticoagulants in Patients with Atrial Fibrillation
JO  - Journal of cardiorespiratory research/Kardiorespirator tadqiqotlar jurnali
PY  - 2023
VL  - 4
IS  - 4
ER  -