Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali Том 11 № 1 (2026)
THE ROLE OF VITAMIN D STATE IN DETERMINING THE SEVERITY AND EFFECTIVENESS OF INPATIENT TREATMENT OF RECURRENT RESPIRATORY TRACT INFECTIONS IN YOUNG CHILDREN
ХАЙДАРОВ Хусан Анварович
Аннотация
The results of this study confirm the feasibility of a comprehensive assessment of vitamin D and CRP levels in young children with recurrent respiratory tract infections in a hospital setting. Vitamin D deficiency and insufficiency were found in 64.7% of children, with severe deficiency occurring in 32.0%. Patients with severe disease had statistically significantly lower 25(OH)D levels and higher CRP concentrations compared to those with moderate disease (p<0.01–0.001). Low vitamin D levels are associated with a longer febrile period, longer hospital stays, and a higher need for oxygen therapy (OR=2.85). An inverse correlation was found between vitamin D levels and CRP (r=−0.45; p<0.01). Using these indicators in clinical practice not only allows for a deeper understanding of the pathogenesis of RITIs but also improves the accuracy of early risk stratification, which is important for optimizing treatment strategies and preventing severe forms of the disease.
дети раннего возраста; рецидивирующие инфекции дыхательных путей; витамин D; 25(OH)D; С-реактивный белок; тяжесть течения; стационарное лечениеyoung children; recurrent respiratory tract infections; vitamin D; 25(OH)D; C-reactive protein; disease severity; inpatient treatmentyosh bolalar; takroriy nafas yo'llari infektsiyalari; D vitamini; 25(OH)D; C-reaktiv oqsil; kasallikning og'irligi; statsionar davolanish
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