Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research Volume 6 Issue 2 (2025)
THE ROLE OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 AND CYSTATIN C IN THE PATHOGENESIS AND DIAGNOSIS OF DIFFERENT FORMS OF GUILLAIN-BARRÉ SYNDROME
Саттарова Сабина Завкиевна, Азизова Раъно Баходировна
Abstract
Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy characterized by demyelination and axonal damage of peripheral nerves. This study examines the levels of monocyte chemoattractant protein-1 (MCP-1) and cystatin C in patients with different clinical forms of GBS. The results showed a significant increase in MCP-1 and cystatin C levels in patients with acute motor-sensory axonal neuropathy (AMSAN) compared to other forms. These findings suggest the role of these biomarkers in the pathogenesis of GBS and their potential diagnostic value.
синдром Гийена–Барре, моноцитарный хемоаттрактантный белок-1, цистатин С, демиелинизирующая полинейропатия (ОВДП), аксональные формы (ОМСАН, ОМАН), биомаркерыGuillain-Barré syndrome, monocyte chemoattractant protein-1, cystatin C, demyelinating polyneuropathy (AIDP), axonal forms (AMSAN, AMAN), biomarkersGiyen-Barre sindromi, monotsitar xemoattraktant oqsil-1, sistatin S, demiyelinizatsiyalovchi polineyropatiya (OVDP), aksonal shakllar (OMSAN, OMAN), biomarkerlar
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